What hypertension medications are safe in pregnancy?

The choice of antihypertensive drugs also is discussed; methyldopa, labetalol, and nifedipine, among others, appear safe for use in pregnancy, whereas angiotensin converting enzyme inhibitors and angiotensin receptor blockers should be avoided.

What hypertension medication is safe during pregnancy?

Methyldopa has been used for decades to treat high blood pressure in pregnancy and it appears to be safe. Labetalol has been extensively studied and has become increasing prescribed in pregnancy. Labetalol is now commonly used as a first-line treatment choice.

Which antihypertensive is not safe in pregnancy?


Table 1 Antihypertensive drugs to avoid in pregnancy and preconception
ACE inhibitors Contraindicated
Angiotensin receptor blockers Contraindicated
Diuretics Avoid

Which drug is preferred for treatment of hypertension in pregnancy describe why?

The only definitive therapy for preeclampsia is delivery. When urgent control of BP is necessary, or when delivery is expected within the next 48 hours, intravenous agents, such as labetalol or hydralazine, are the drugs of choice.

Is amlodipine safe in pregnancy?

Amlodipine and Pregnancy

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Amlodipine falls into category C. There are no good studies in pregnant women. Amlodipine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known if amlodipine will harm your unborn baby.

Can I take blood pressure meds while pregnant?

Some blood pressure medications are considered safe to use during pregnancy, but angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers and renin inhibitors are generally avoided during pregnancy.

Is atenolol safe in pregnancy?

It is concluded that atenolol and labetalol are safe and they are usually effective in the control of the hypertension complicating pregnancy.

What is the first drug of choice for hypertension?

The strongest body of evidence indicates that for most patients with hypertension, thiazide diuretics are the best proven first-line treatment in reducing morbidity and mortality.

Which is the safest antihypertensive drug?

Though angiotensin receptor blockers are the most commonly prescribed medication type, they found that thiazides were the safest and most effective while calcium channel blockers exhibited the least effective outcomes.

Is losartan safe during pregnancy?

Do not take losartan if you are pregnant. If you become pregnant while you are taking losartan, stop taking losartan and call your doctor immediately. Losartan may cause death or serious injury to the fetus when taken in the last 6 months of pregnancy.

Is Clonidine safe during pregnancy?

Clonidine hydrochloride, like methyldopa, appears to be a safe antihypertensive agent in pregnancy.

Is HCTZ safe in pregnancy?

Experts recommend avoiding hydrochlorothiazide, or HCTZ (Aquazide H, Diaqua, Hydrocot and others) during pregnancy unless its benefits clearly outweigh its potential risks. HCTZ has not been studied well in pregnant women, but it is known to pass through the placenta to a developing fetus.

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Is chlorthalidone safe during pregnancy?

Taking chlorthalidone during pregnancy may cause side effects in the newborn baby, such as jaundice (yellowing of the skin or eyes), bruising or bleeding, low blood sugar, or an electrolyte imbalance. Do not start or stop taking chlorthalidone during pregnancy without your doctor’s advice.

Can I take indomethacin while pregnant?

Women who are more than 32 weeks pregnant should avoid taking indomethacin, given the potential for heart problems in the baby. Women with a history of ulcers, bleeding disorders, or kidney or liver disease should also avoid taking indomethacin.

Is hydralazine safe in pregnancy?

Oral hydralazine, a direct vasodilator, is effective as monotherapy or as add-on therapy to methyldopa in the long term management of chronic hypertension in pregnancy. Hydralazine appears to be reasonably safe for the fetus although a few cases of fetal thrombocytopenia have been reported.